Genotype concordance between Illumina, Complete Genomics and BGI-seq platforms

less than 1 minute read

Published:

Based on PCA, an overview of the genotype concordance between Illumina ultra high-coverage (~200x), Illumina high-coverage (~30x), Illumina low-coverage (~7x), Complete Genomics high-coverage (versions 2.0 and 2.2, from ~30x to ~87x) and BGIseq-500 high-coverage (PE100, ~37x) platforms/sequencing-runs. For this purpose I used 12 reference samples for which there are available data in at least two or more of the previous technologies.

References:

IGSR: The International Genome Sample Resource

genome-in-a-bottle

Complete Genomics - Public Genome Data Repository

The PE150 reference human genome dataset of the BGISEQ-500 and NovaSeq6000 sequencer